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Effect of Positive End Expiratory Pressure on intracranial pressure in the neurosurgical patients with the supratentorial tumor

Evaluation and comparison of intracranial pressure in the patients with supra tentorial tumor According to different the positive end expiatory pressure applied during tumor surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017041912782N14
Enrollment
66
Registered
2017-05-15
Start date
2016-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

supratentorial. Benign neoplasm: Brain, supratentorial

Interventions

Intervention 1: The intervention group 1: patients who have 0 cmH2O Positive End Expiratory Pressure. Intervention 2: The intervention group 2: patients who have 5 cmH2O Positive End Expiratory Press
Treatment - Devices
The intervention group 1: patients who have 0 cmH2O Positive End Expiratory Pressure
The intervention group 2: patients who have 5 cmH2O Positive End Expiratory Pressure
The intervention group 3: patients who have 10 cmH2O Positive End Expiratory Pressure

Sponsors

Vice chancellor for research,Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: neurosurgical patients with supratentorial tumor; Ages 18 to 60 years; Without having hypertension or diabetes; No history of stroke or heart failure. Exclusion criteria: patients with lung diseases such as asthma and chronic obstructive pulmonary disease; Brain shifts to the more than 5 mm from the mid line; Severe hydrocephalus; Loss of consciousness; Closed brain solcus, severe headache; Nausea and vomiting.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Intracranial pressure. Timepoint: Before and after the intervention. Method of measurement: Touching the dura mater.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Vahid Salimi

Isfahan University of Medical Sciences

vahid.salimi79@yahoo.com+98 316680048

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026