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Evaluation of the effect of tadalafil on the treatment of acute urinary retention

Survey the addition of tadalafil to tamsulosin in the treatment of acute urinary retention in patient with benign prostatic hyperplasia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017041833506N1
Enrollment
80
Registered
2017-09-13
Start date
2016-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute urinary retention. Hyperplasia of prostate

Interventions

Intervention 1: In the intervention group, 10 mg Tadalafil tablets plus 0.4 mg Tamsulosin capsule once a day for seven days. Intervention 2: Placebo pills (in the same way, the size and color of tadal
Treatment - Drugs
Placebo
In the intervention group, 10 mg Tadalafil tablets plus 0.4 mg Tamsulosin capsule once a day for seven days
Placebo pills (in the same way, the size and color of tadalafil made from starch) with Tamsulosin capsules 0.4 milligrams per night for one week

Sponsors

Sabzevar University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
45 Years to 6 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients who refused to participate in the study and signed informed consent form; Age over 50 years;Symptoms of LUTS or urinary tract symptoms.Exclusion criteria: Discontent of continued cooperation with the study for any reason and at any stage of the research; Age less than 50 years; Proven history of prostate cancer; Prostatitis; Urethral obstruction caused by tumor; known tumor disease caused by lower urinary tract (bladder stones, neurogenic bladder, bladder cancer, urethral stricture); Surgery lower urinary tract (bladder, prostate and urethra); Nitrate consumption at the same time; Acute urinary retention after surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Acute Urinary Retention. Timepoint: 24 hours and one week after the intervention. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeinab Ameli

Sabzevar University of Medical Sciences

zameli_2010@yahoo.com+98 51 3859 6778

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026