Comparison of the effect of vaginal versus sublingual misoprostol in medical induction of missed abortions

Comparison of the effect of vaginal versus sublingual misoprostol in medical induction of missed abortions: a randomized clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201704179014N159

Enrollment

100

Registered

2017-04-30

Start date

2017-05-05

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Missed abortion. Missed abortion

Interventions

Intervention 1: Intervention group 1: Tablet misoprostol 600 micgr sublingually single dose and if bleeding does not begin after 6 hours, the same dose will be repeated. Intervention 2: Intervention g

Treatment - Drugs

Intervention group 1: Tablet misoprostol 600 micgr sublingually single dose and if bleeding does not begin after 6 hours, the same dose will be repeated.

Intervention group 2: Tablet misoprostol 600 micgr vaginally single dose and if bleeding does not begin after 6 hours, the same dose will be repeated.

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age of 18 to 40 years; gestational age 6 to 14 weeks; missed abortions. Exclusion criteria: Previous cesarean; systemic diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Bleeding and abortion. Timepoint: 3, 6, and 12 hours after intervention. Method of measurement: thorough physical examination.;Remaining vestiges of pregnancy or incomplete abortion. Timepoint: 12 hours after intervention. Method of measurement: by sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMina Ajand

Fatemieh Hospital

ajandmina@Gmail.com+98 81 3828 3939

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026