Evaluation effect of human chorionic gonadotropin on pregnancy outcome in infertile patients

Evaluation effect of intrauterine injection of human chorionc gonadotropin before embryo transfer on implantation rate and pregnancy rate in frozen cycles on IVF/ICSI

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017041733486N1

Enrollment

300

Registered

2017-10-13

Start date

2017-10-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: IVF. Condition 2: ICSI. Condition 3: Infertility. In vitro fertilization Admission for harvesting or implantation of ova Artificial insemination Complications of attempted introduction of embryo in embryo transfe

Interventions

Intervention 1: Control group: The second group (n 130) did not receive the administration of 500 IUhCG. Intervention 2: Interventional group (n 130) was injected with 500 UI of intrauterine hCG befo

Treatment - Drugs

Control group: The second group (n 130) did not receive the administration of 500 IUhCG.

Interventional group (n 130) was injected with 500 UI of intrauterine hCG before embryo transfer.

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Exclusion criteria:patients with a history of utrine surgery such as myomectmy;Patients with a history of recurrent miscarriage;Patients with known hydrosalpinx;Patients with endometriosis and endometroma;Patients with history of RIF(>3);Patients >40 years ;Inclusion criteria:All patients under age 40 years who refer to Omid fertility centre and shariati hospital who suffered from infertility.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Embryo implantation. Timepoint: 4 weeks after transfer. Method of measurement: Sonography.;Chemical pregnancy. Timepoint: 2 weeks after transfer. Method of measurement: pregnancy test(BHCG test).;Clinical pregnancy. Timepoint: 4-5 weeks after emberyo transfer. Method of measurement: observation of fetal heart activity by transvaginal ultrasonography.	—

Secondary

Measure	Time frame
Abortion. Timepoint: 2-4 weeks after transfer. Method of measurement: By sonography,clincal finding, pregnancy test.;Ectopic pregnancy. Timepoint: 4weeks after transfer. Method of measurement: by sonography ,pregnancy test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZiaee Zohreh

Tehran University

ziaee-z@razi.tums.c.ir+98 21 8889 6692

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026