ischemic stroke. Cerebral infarction
Conditions
Interventions
Intervention 1: Atorvastatin = 40 mg/day.oral, Coadministration with CoQ10= 300 mg/day
Three times a day. 30 days. oral. Intervention 2: Atorvastatin= 40 mg/day,daily
30 days, oral.
Treatment - Drugs
Atorvastatin = 40 mg/day.oral, Coadministration with CoQ10= 300 mg/day
Three times a day. 30 days. oral.
Atorvastatin= 40 mg/day,daily
30 days, oral
Sponsors
Vice chancellor for research, Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (patients with ischemic stroke involving the middle cerebral artery, confirmed by computed tomography scanning and clinical symptoms; range of age 50-70 years; not to receive statins continuously before entering the study; not to receive antioxidants (such as vitamin C and E) constantly; not to receive anti-inflammatory drugs (steroids, nonsteroidal anti-inflammatory) constantly; not affected by AIDS and neurodegenerative diseases (e.g. Alzheimer's, Parkinson's, amyotrophic lateral sclerosis, multiple sclerosis); no loss of consciousness level due to any reason except stroke (such as shock, alcohol consumption or intoxication); non-pregnancy; non-epilepsy; patient`s consent).Exclusion criteria: (patient's death during the study; lack of patient`s availability to follow-up; no tendency to attend in next follow-up).
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of disability. Timepoint: Admission- After 30 day. Method of measurement: Modified Rankin Scale (MRS).;Glial fibrillary acidic protein(GFAP). Timepoint: admission- 72 houre-after 30 day. Method of measurement: eliza kit.;Cognitive performance. Timepoint: admission- 72 houre-after 30 day. Method of measurement: Mini-Mental State Examination(MMSE).;Motor function and verbal. Timepoint: admission- 72 houre-after 30 day. Method of measurement: National Institutes of Health Stroke Scale(NIHSS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLeila Simani
Shahid Beheshti University of Medical Sciences
Outcome results
None listed