Study the effect of Bupivacaine 0.5% , Lidocaine 5%, Pethidine , Lidocaine 5% & intratecal on the incidence of decrease blood pressure, nausea and vomiting for elective caesarean section

Comparison of the effect of Bupivacaine 0.5% , Lidocaine 5% , Pethidine , Lidocaine 5% & intratecal on the incidence of decrease blood pressure , nausea and vometing for elective caesarean section

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170417033491N2

Enrollment

Registered

2018-08-09

Start date

2017-10-04

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caesarean Section. Delivery by elective caesarean section

Interventions

Intervention 1: Patients in group one received lidocaine 5% - pethedine (60 mg lidocaine 5% -15 mg pethedine as local anesthetic. Intervention 2: Patients in group two received 75 mg lidocaine 5% as l

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age 45 - 18 years Term pregnancy (42-37 weeks) Willingness to participate in the study NPO (Nil Per Os) ASA I Elective caesarean section

Exclusion criteria

Exclusion criteria: Operation duration more than 80 minutes Using ritodrine or other beta tocolytic Fetal abnormalities or pregnancy complications Failure in performing spinal Low level of blocks (block level lower than T8) Stomachache; metabolic diseases; hypertension; nausea and vomiting before surgery Any underlying diseases Complications during surgery Arterial or venous disease in lower extremities Defects in the immune system and gestational diabetes Smoking Alcoholism and opium addiction Malnutrition Anemi

Design outcomes

Primary

Measure	Time frame
Percentage of people who have nausea and vomiting during surgery. Timepoint: During surgery and then until the end of the recovery. Method of measurement: Observasion.;Blood Pressure. Timepoint: Measure and record pulse rate, mean, systolic and diastolic blood pressure immediately after the block (during surgery) every 3 to 15 minutes and then every 5 minutes until the end of the recovery. Method of measurement: Automatic sphygmomanometer.	—

Measure

Time frame

Percentage of people who have nausea and vomiting during surgery. Timepoint: During surgery and then until the end of the recovery. Method of measurement: Observasion.;Blood Pressure. Timepoint: Measure and record pulse rate, mean, systolic and diastolic blood pressure immediately after the block (during surgery) every 3 to 15 minutes and then every 5 minutes until the end of the recovery. Method of measurement: Automatic sphygmomanometer.

—

Secondary

Measure	Time frame
Itching. Timepoint: Every 3 to 15 minutes and then every 5 minutes until the end of the recovery. Method of measurement: Observasion.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJalal Saem

Gerash University of Medical Sciences

saemj@sums.ac.ir+98 71 5244 8108

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026