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The effect of gabapentin supplementation in ureteral stone patients

Evaluation of the increasing effect of gabapentin supplementation on standard (anticholinergic) treatment in controlling stimulus symptoms after double J stent placement in ureteral stone patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170417033489N8
Enrollment
76
Registered
2021-07-05
Start date
2021-06-22
Completion date
Unknown
Last updated
2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ureteral stone disease. Presence of urogenital implants

Interventions

Intervention 1: Intervention group: Treated with anticholinergics and gabapentin 100 mg orally once daily. Solifenacin 5 mg orally is used as an anticholinergic drug. After 2 weeks from the start of t

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with unilateral ureteral stones more than 15 mm in diameter who have undergone TUL lithotripsy Patients should be over 18 years old A double G catheter is installed for them

Exclusion criteria

Exclusion criteria: Chronic use (more than 3 months) of alpha-blocker and analgesic drugs History of neurogenic bladder Recurrent urinary tract infections Chronic pelvic pain Patient dissatisfaction Leaving the study during the study process People who are contraindicated in gabapentin History of previous allergy to gabapentin Pregnancy Breastfeeding Liver failure Renal failure People who are in the high-risk group due to the drowsiness complication of the drug

Design outcomes

Primary

MeasureTime frame
Score obtained based on the patient's irritating symptoms questionnaire. Timepoint: Before intervention and 14 days after gabapentin. Method of measurement: ureteral stent symptom questionnaire (USSQ).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Salman Soltani

Mashhad University of Medical Sciences

soltanis@mums.ac.ir+98 51 3858 3885

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026