The effect of LHRH agonist on urinary retention

The effect of LHRH agonist on the improvement of urinary retention compared with the effect of finasteride and tamsulosin alone

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170417033489N3

Enrollment

Registered

2019-10-17

Start date

2019-10-22

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute urinary retention in patients with BPH. Enlarged prostate

Interventions

Intervention 1: Intervention group: All patients will receive routine BPH treatment including alpha-blocker tamsulosin 0.4 mg single daily oral and alpha reductase inhibitor finasteride 5 mg single da

Eligibility

Sex/Gender

Male

Age

50 Years to No maximum

Inclusion criteria

Inclusion criteria: The first acute urinary retention No other treatment No indication of surgery Patient's urinary retention is caused by BPH Minimum age of 50 years

Exclusion criteria

Exclusion criteria: Informed patient dissatisfaction History of any heart, liver, kidney, metabolic and seizure diseases Patients with fever mean T more than 38 degrees Celsius High PSA levels (above 4) which strengthen suspicion of prostate cancer

Design outcomes

Primary

Measure	Time frame
The amount of post voiding residue(PVR). Timepoint: One day after leaving the cathedral. Method of measurement: Ultrasound.;The rate of catheter release in acute urinary retention induced by BPH. Timepoint: One month after drug injection. Method of measurement: No need for re-catheterization.;IPSS Score. Timepoint: Before and one month after drug injection. Method of measurement: IPSS Questionnaire.;The incidence of drug side effects. Timepoint: One month after drug injection. Method of measurement: Ask the patient.	—

Measure

Time frame

The amount of post voiding residue(PVR). Timepoint: One day after leaving the cathedral. Method of measurement: Ultrasound.;The rate of catheter release in acute urinary retention induced by BPH. Timepoint: One month after drug injection. Method of measurement: No need for re-catheterization.;IPSS Score. Timepoint: Before and one month after drug injection. Method of measurement: IPSS Questionnaire.;The incidence of drug side effects. Timepoint: One month after drug injection. Method of measurement: Ask the patient.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSalman Soltani

Mashhad University of Medical Sciences

soltanis@mums.ac.ir+98 51 3802 2553

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026