Comparison of the efficacy of intranasal mupirocin ointment with povidone iodine solution on the colonization of Staphylococcus aureus

Comparison of the Efficacy of Intranasal Mupirocin Ointment with Povidone Iodine Solution on the Colonization of Staphylococcus aureus among Carrier Patients and Medical Staff

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170417033487N2

Enrollment

Registered

2022-05-13

Start date

2022-06-22

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Staphylococcus aureus carriers in the nasal cavity. Staphylococcus aureus as the cause of diseases classified to other chapters

Interventions

Intervention 1: Intervention group: Group A receives mupirocin ointment (topically in the nasal cavity twice daily) for five days. Intervention 2: Intervention group: Group B receives povidone iodine

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing hemodialysis in the dialysis ward of the hospital; or staff working in the hemodialysis, intensive care, operating room and infectious wards of the hospital Positive culture of nasal specimens for Staphylococcus aureus

Exclusion criteria

Exclusion criteria: Immunocompromised patients Antibiotic consumption in the last 1 month History of Hypersensitivity to intranasal mupirocin ointment or povidone iodine solution Corticosteroids consumption

Design outcomes

Primary

Measure	Time frame
Colonization of Staphylococcus aureus in the nasal cavity. Timepoint: Sixth day after the start of the intervention. Method of measurement: Laboratory report (culture in trypticase soy broth).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Sara Abolghasemi

Shahid Beheshti University of Medical Sciences

saraabolghasemi@sbmu.ac.ir+98 21 2360 2280

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026