Providing an optimal protocol using virtual reality exposure therapy and repetitive transcranial magnetic stimulation for post-traumatic stress disorder

Providing an optimal protocol using virtual reality exposure therapy and repetitive transcranial magnetic stimulation for post-traumatic stress disorder: A double-blind, randomized, sham-controlled clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170417033485N8

Enrollment

110

Registered

2026-05-03

Start date

2026-05-10

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-traumatic stress disorder (PTSD). Post-traumatic stress disorder (PTSD)

Interventions

Intervention 1: Control group (Sham group): Present in the first phase of the study to identify the best brain region and stimulation protocol, this group will include PTSD patients who will be attach

Eligibility

Sex/Gender

Male

Age

25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age between 25 and 65 years old Being male Physical health Right-handed

Exclusion criteria

Exclusion criteria: Vertigo headache Presence of systemic diseases

Design outcomes

Primary

Measure	Time frame
Clinician-Administered PTSD Scale (CAPS) score. Timepoint: Pretest-Posttest-Follow-up. Method of measurement: The Clinician-Administered PTSD Scale (CAPS) is a structured method of history-taking administered by a physician or therapist in the form of an interview. In this questionnaire (30 items in the validated Persian version), the interviewer asks the patient about their everyday experiences and general states, and the individual's score is calculated based on a Likert scale to measure symptom severity.;PTSD checklist (PCL) score. Timepoint: Pretest-Posttest-Follow-up. Method of measurement: The PTSD checklist (PCL) is a 20-item self-report questionnaire (17 items in the available Persian version) completed by the patient. The items address the individual's symptoms of the disorder and their experience in daily life. Each item is scored on a 5-point Likert scale ranging from "not at all" (1) to "extremely" (5). The total score is calculated by summing all item scores, and individuals scoring above a specified cut-off point (typically 50 for military personnel) are considered to have PTSD symptoms.	—

Measure

Time frame

Clinician-Administered PTSD Scale (CAPS) score. Timepoint: Pretest-Posttest-Follow-up. Method of measurement: The Clinician-Administered PTSD Scale (CAPS) is a structured method of history-taking administered by a physician or therapist in the form of an interview. In this questionnaire (30 items in the validated Persian version), the interviewer asks the patient about their everyday experiences and general states, and the individual's score is calculated based on a Likert scale to measure symptom severity.;PTSD checklist (PCL) score. Timepoint: Pretest-Posttest-Follow-up. Method of measurement: The PTSD checklist (PCL) is a 20-item self-report questionnaire (17 items in the available Persian version) completed by the patient. The items address the individual's symptoms of the disorder and their experience in daily life. Each item is scored on a 5-point Likert scale ranging from "not at all" (1) to "extremely" (5). The total score is calculated by summing all item scores, and individuals scoring above a specified cut-off point (typically 50 for military personnel) are considered to have PTSD symptoms.

—

Secondary

Measure	Time frame
Clinical signs of PTSD. Timepoint: Pretest-Posttest-Follow-up. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Alireza Mohammadi

Bagheiat-allah University of Medical Sciences

ar.mohammadi@bmsu.ac.ir+98 21 2612 7281

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026