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Investigating the effect of High-Density Transcranial Electrical Stimulation (HD-tDCS) over the ventromedial prefrontal cortex (vmPFC) in improving emotion regulation strategies

Investigating the effect of High-Density Transcranial Electrical Stimulation (HD-tDCS) over the ventromedial prefrontal cortex (vmPFC) in improving emotion regulation strategies and reappraisal planning in healthy individuals: A double-blind, randomized, sham-controlled clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170417033485N5
Enrollment
50
Registered
2025-12-21
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

emotion dysregulation. Other persistent mood [affective] disorders

Interventions

Intervention 1: Control (Placebo) group: In this group, a pre-test including the PASAT test and questionnaires are taken for the baseline condition, and after a week to 10 days, the HD-tDCS device is

Sponsors

Bagheiat-allah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age range 18 to 45 Male gender Being right-handed Absence of underlying systemic diseases and neurological and mental disorders No history of taking any medication regularly No history of drug or stimulant substances use

Exclusion criteria

Exclusion criteria: Lack of willingness or ability to complete the test stages Suffering from a disease or any special condition during the trial Intolerance of HD-tDCS stimulation

Design outcomes

Primary

MeasureTime frame
Difficulties in Emotion Regulation Scale Questionnaire Score. Timepoint: Before the intervention (Pre-test) and after the intervention (Post-test). Method of measurement: Difficulties in Emotion Regulation Scale (DERS) Questionnaire.;Emotion Regulation Questionnaire Score. Timepoint: Before the intervention (Pre-test) and after the intervention (Post-test). Method of measurement: Emotion Regulation Questionnaire (ERQ).

Secondary

MeasureTime frame
Cognitive Emotion Regulation Questionnaire Score. Timepoint: Before the intervention (Pre-test) and after the intervention (Post-test). Method of measurement: Cognitive Emotion Regulation Questionnaire (CERQ).;Paced Auditory Serial Addition Test Score. Timepoint: Before the intervention (Pre-test) and after the intervention (Post-test). Method of measurement: Paced Auditory Serial Addition Test (PASAT).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Alireza Mohammadi

Bagheiat-allah University of Medical Sciences

ar.mohammadi@bmsu.ac.ir+98 21 2612 7281

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026