The effect of combined transcranial electrical stimulation and schema therapy on major depressive disorder

The Effect of the combined effect of transcranial direct electrical stimulation and schema therapy on cognitive and clinical symptoms of patients with major depressive disorder: A double-blind, randomized, sham-controlled clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170417033485N4

Enrollment

Registered

2025-11-16

Start date

2025-11-22

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depressive disorder.

Interventions

Intervention 1: Intervention Group 1: Schema Therapy. This intervention consists of twelve one-hour sessions conducted by a counselor, with one-week intervals between sessions. Schema therapy is an in

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Obtaining a score higher than 29 on the Beck Depression Inventory (BDI-II)

Exclusion criteria

Exclusion criteria: Unwillingness to begin or continue participating in the research Having other mental or neurological disorders

Design outcomes

Primary

Measure	Time frame
Depression score on the Beck Depression Inventory. Timepoint: At the beginning and end of the study. Method of measurement: Beck Depression Inventory.	—

Secondary

Measure	Time frame
Clinical signs of depression. Timepoint: The beginning and end of the study. Method of measurement: Individual observation and reporting - Young's Schema Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Alireza Mohammadi

Bagheiat-allah University of Medical Sciences

ar.mohammadi@bmsu.ac.ir+98 21 2612 7281

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026