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Comparison of chlorhexidine? normal saline, and nystatin in prevention of oral candidiasis in ICU admitted patients of Tohid hospital of sanandaj

Comparison of the effect of chlorhexidine, normal saline and nystatin in the prevention of oral candidiasis in patients admitted to the ICU of Tohid Hospital in Sanandaj

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170417033483N3
Enrollment
45
Registered
2020-10-05
Start date
2020-10-22
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral candidiasis. Candidal stomatitis

Interventions

Intervention 1: Intervention group: Chlorhexidine mouthwash every 12 hours for 14 days. Intervention 2: Intervention group: Nystatin mouthwash every 12 hours for 14 days. Intervention 3: Control group

Sponsors

Sanandaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients admitted to the intensive care unit

Exclusion criteria

Exclusion criteria: Clinical oral candidiasis Existence of more than 50 Candida colonies at the time of admission The patient's condition is such that he is likely to stay in the ICU for less than 5 days. Existence of any oral diseases Lack of patient cooperation until the end of the hospitalization period

Design outcomes

Primary

MeasureTime frame
Oral infection with Candida albicans yeast in more than 50 colonies. Timepoint: In 4 stages of admission, on the 5th day and on the 10th and 14th day of admission, sample patients are taken for colony count, respectively. Method of measurement: Patients are forbidden to eat or drink for at least 2 hours before sampling. Sterile swabs are stretched with relatively strong movement on the palate, tongue and cheeks and are immediately transferred to the culture medium.

Secondary

MeasureTime frame
Oral diseases. Timepoint: Daily every 12 hours. Method of measurement: observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHero azizzadeh

Sanandaj University of Medical Sciences

Heroazizzadeh@yahoo.com+98 87 1613 1281

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026