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Comparison the effect of two days interval amikacin with standard therapy in treatment of urinary tract infection

Comparison the effect of two days interval amikacin with standard therapy in treatment of urinary tract infection

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170417033483N2
Enrollment
200
Registered
2018-02-13
Start date
2017-05-22
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

UTI. Urinary tract infection, site not specified

Interventions

Intervention 1: Intervention group ESBL: Each 48 hours of amikacin is given 3mg / kg / Q48 hours for 7 days, and then treatment of Ofloxacin 300 mg twice daily for 7 days is continued. Intervention 2:

Sponsors

Kurdistan university of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with symptoms of burning up urine Patients with frequent urinary symptoms Patients with urinary symptoms and fever

Exclusion criteria

Exclusion criteria: Use of antibiotics over the last week Stage I and above CKD pregnancy septic shock use of immuno suppressive drugs Increased patient creatinine by more than 3 or more than 50% relative to the original creatinine during treatment

Design outcomes

Primary

MeasureTime frame
Urinary tract infection(UTI). Timepoint: 7 days after the start of treatment, intravenous and oral treatment phase (7 days. Method of measurement: Urine analysis and urina culture.;Clinical symptoms of UTI. Timepoint: 48 hours and 1 week after the end of therapy with intravenous and oral treatment. Method of measurement: By patient symptoms and clinical findings.

Secondary

MeasureTime frame
Adverse Drug Reactions. Timepoint: 48 hours and 1 week after treatment and at the end of intravenous and oral treatment. Method of measurement: Clinical symptoms and examination findings, laboratory.

Countries

Iran (Islamic Republic of)

Contacts

Public Contacthero azizzadeh

Kurdistan University of Medical Sciences

h.azizzadeh@muk.ac+98 87 3366 4645

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026