Skip to content

The Comparison of effect of Valuven versus ringer solution in cardiopulmonary bypass prime on the postoperative bleeding and renal function in coronary artery bypass graft surgery

The Comparison of effect of Valuven versus ringer solution in cardiopulmonary bypass prime on the postoperative bleeding and renal function in coronary artery bypass graft surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017041519470N56
Enrollment
60
Registered
2017-04-21
Start date
2017-04-16
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Bypass Surgery. Atherosclerotic heart disease

Interventions

Intervention 1: Patients in group A received 1500 cc Ringer as a prime solution during preparation of (CPB). Intervention 2: Patients in group B received Valuven1500 ml, 130/04 (hydroxyethyl starch) d
Treatment - Drugs
Patients in group A received 1500 cc Ringer as a prime solution during preparation of (CPB).
Patients in group B received Valuven1500 ml, 130/04 (hydroxyethyl starch) during preparation of CPB. Monitoring of vital signs is recorded.

Sponsors

Vice Chancellor for Research, Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients undergoing coronary artery bypass graft (CABG) for the first time. Exclusion criteria: undergoing cardiac surgery for the second time; emergency coronary artery bypass; coagulation disorders prior to surgery; the preoperative clopidogrel (Plavix); congestive heart failure before surgery; renal failure before surgery (creatinine greater than (1 / 3) with a previous history of heart surgery; heart failure; coagulation disorders including abnormal PT and PTT, INR, PLAT; kidney disease included high chromium 1.3 and taking Plavix (clopidogrel).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Bleeding. Timepoint: during and after surgery. Method of measurement: Observasion.

Secondary

MeasureTime frame
Lab data (CR - Na-K -HB- hematocrit- PT- PTT-INR ). Timepoint: before surgery and 24 hours after surgery in the ICU. Method of measurement: blood sample.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElahe allahyari

Shiraz University of Medical Sciences

allahyarye@sums.ac.ir+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026