Patients with cholecystitis. Calculus of gallbladder with acute cholecystitis
Conditions
Interventions
Intervention 1: Intervention group: After preparation of the surgical site and before surgical incision (for laparoscopic trochar passage and CO2 gas blowing), Ketamine is injected at a dose of 0.5mg/
Sponsors
Gorgan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients with Class 1 and 2 physical activity according to the American Society of Anesthesiologists (ASA1, 2) who have completed the consent form Age range 18-60 years
Exclusion criteria
Exclusion criteria: Abuse of drugs or opioids or psychotropic drugs A history of seizures or taking anticonvulsants Sensitivity to ketamine or anesthetic induction drugs A history of high Intra cranial pressure (ICP) Patients with BMI=40
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain. Timepoint: During the first 24 hours after surgery. Method of measurement: By Visual Analogue Scale (Score 1-10, 1=No pain, 10= worst pain).;The amount of opioids consumption. Timepoint: During the first 24 hours after surgery. Method of measurement: The total dose of the drug administrated.;Changes in Systolic and diastolic blood pressure. Timepoint: After blowing gas into the peritoneal cavity and during the surgery. Method of measurement: Measurement of systolic and diastolic blood pressure by a barometer in millimeters of mercury (mmHg).;Changes in mean arterial pressure. Timepoint: After blowing gas into the peritoneal cavity and during the surgery. Method of measurement: Mean arterial pressure in millimeters of mercury (mmHg), measured by systolic blood pressure and diastolic blood pressure by a barometer and calculate through Mean arterial pressure = systolic blood pressure + 2(diastolic blood pressure)/3. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Babak Mojaver Aghili
Gorgan University of Medical Sciences
Outcome results
None listed