hemoldialysis. Extracorporeal dialysis
Conditions
Interventions
Prevention
Placebo
Intervention 1: Probiotics supplementation with one 5 gr Probiotics saches (105 bifidobacter and lactobacilus) and two 5 gr sache of maltodextrin. Intervention 2: Synbiotics supplementation with two 5
Probiotics supplementation with one 5 gr Probiotics saches (105 bifidobacter and lactobacilus) and two 5 gr sache of maltodextrin
Synbiotics supplementation with two 5 gr sache of prebiotics (FOS, GOS, Inulin) and one 5 gr sache of probiotics (105 lactobasilus, bifidobacter)
Placebo cantaining three 5 gr saches of maltodextrin
Sponsors
Vice chancellor for research, Ahvaz Jundishapour University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria were: willingness to cooperate; at least 3 months renal failure on hemodialysis, 4 hours hemodialysis three times a week; aged between 65-30 years Exclusion criteria: history of kidney transplantation; infection; history of hospitalization in the last month; useing any products or supplements containing probiotics and prebiotics and antibiotics in 1 months; using vitamins fiber omega-3 antioxidants within 3 weeks before or during the study; using nonsteroidal anti-inflammatory drug NSAIDs; progesterone, immunosuppressive drugs; diuretics and corticosteroids; the radiation in the area of small and large bowel; with Being irritable bowel syndrome; Crohn's disease or ulcerative colitis; a severe malnutrition (SGA: C); swelling and bloating
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ?Antibody HSP70. Timepoint: at first and two months after intervention. Method of measurement: ELISA.;Interleukin -6. Timepoint: at first and two months after intervention. Method of measurement: ELISA.;ICAM-1. Timepoint: at first and two months after intervention. Method of measurement: ELISA.;VCAM-1. Timepoint: at first and two months after intervention. Method of measurement: ELISA.;Cytokeratin-18. Timepoint: at first and two months after intervention. Method of measurement: ELISA.;Endotoxin. Timepoint: at first and two months after intervention. Method of measurement: ELISA.;BUN. Timepoint: at first and two months after intervention. Method of measurement: Enzymatic.;Keratinin. Timepoint: at first and two months after intervention. Method of measurement: Enzymatic.;Hs-CRP. Timepoint: at first and two months after intervention. Method of measurement: ELISA.;The number of Lactobacillus colonies. Timepoint: at first and two months after intervention. Method of measurement: dilution.;The number of bifidobacter colonies. Timepoint: at first and two months after intervention. Method of measurement: dilution. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNeda Haghighat
Ahvaz Jundishapour University of Medical Sciences
Outcome results
None listed