Assessing of the lidocaine oropharyngeal spray before tracheal intubation on heart rate, blood pressure and arrhythmia in patients undergoing coronary artery bypass graft.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170411033365N3

Enrollment

Registered

2022-03-15

Start date

2022-04-04

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with cardiac ischemia undergoing CABG.

Interventions

Intervention 1: Intervention group: In the LS group, two puffs of lidocaine 10% spray were used before induction of anesthesia and two puffs were used before laryngoscopy for endotracheal intubation.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients due to cardiac ischemia undergoing CABG

Exclusion criteria

Exclusion criteria: Patients with a history of previous arrhythmias (Atrial Fibrilation) AF Have cardiomyopathy of any cause renal and hepatic impairment, patients with lidocaine hypersensitivity patients requiring repeated efforts due to airway obstruction or endotracheal intubation for any reason

Design outcomes

Primary

Measure	Time frame
Heart rate. Timepoint: baseline (T0), one minute before intervention (T1), 30 seconds (T2) and one minute (T3), two (T4), three (T5) ), Four (T6), five (T7), and 10 (T8) after intervention. Method of measurement: Saadat Cardiac and hemodynamic Monitoring for rate monitoring.;Blood Pressure. Timepoint: baseline (T0), one minute before intervention (T1), 30 seconds (T2) and one minute (T3), two (T4), three (T5) ), Four (T6), five (T7), and 10 (T8) after intervention. Method of measurement: Saadat Cardiac and hemodynamic Monitoring for direct blood pressure monitoring.;Arrhythmia. Timepoint: baseline (T0), one minute before intervention (T1), 30 seconds (T2) and one minute (T3), two (T4), three (T5) ), Four (T6), five (T7), and 10 (T8) after intervention. Method of measurement: Saadat Cardiac and hemodynamic Monitoring for arrhythmia detection.	—

Measure

Time frame

Heart rate. Timepoint: baseline (T0), one minute before intervention (T1), 30 seconds (T2) and one minute (T3), two (T4), three (T5) ), Four (T6), five (T7), and 10 (T8) after intervention. Method of measurement: Saadat Cardiac and hemodynamic Monitoring for rate monitoring.;Blood Pressure. Timepoint: baseline (T0), one minute before intervention (T1), 30 seconds (T2) and one minute (T3), two (T4), three (T5) ), Four (T6), five (T7), and 10 (T8) after intervention. Method of measurement: Saadat Cardiac and hemodynamic Monitoring for direct blood pressure monitoring.;Arrhythmia. Timepoint: baseline (T0), one minute before intervention (T1), 30 seconds (T2) and one minute (T3), two (T4), three (T5) ), Four (T6), five (T7), and 10 (T8) after intervention. Method of measurement: Saadat Cardiac and hemodynamic Monitoring for arrhythmia detection.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Alireza Mahoori

Oroumia University of Medical Sciences

Mahouri.a@umsu.ac.ir+98 44 3346 9931

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026