lovastatin effect in preventing of contrast induced acute kidney injury

Efficacy of short-term high-dose lovastatin in prevention of contrast-induced acute kidney injury in patients receiving intravenous contrast drugs

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017041033359N1

Enrollment

122

Registered

2017-05-15

Start date

2017-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Contrast induced acute kidney injury. Other acute renal failure

Interventions

Intervention 1: In the intervention group, 60 milligrams of lovastatin administered on the day before the procedure, the day of the procedure, and the day after the procedure. Intervention 2: The cont

Treatment - Drugs

In the intervention group, 60 milligrams of lovastatin administered on the day before the procedure, the day of the procedure, and the day after the procedure.

The control group received placebo similar to lovastatin tabletes.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients that need intravenous contrast administration. Exclusion criteria: Acute kidney injury; acute coronary syndrome and acute myocardial infarction; statin sensitivity; patients Dissatisfaction

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Acute kidney injury. Timepoint: Basline and 4h hours after diagnostic intervention. Method of measurement: Serum creatinine and MDRD e GFR.;Acute kidney injury. Timepoint: 48 h after intervention. Method of measurement: Serum creatinine and MDRD e GFR.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKhled fathizadeh

Kurdistan University of Medical Sciences

khaledfathizadeh54@gmail.com+98 87 3328 6117

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026