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Effect of Ketorolac and Paracetamol on Pain Control after Hernia Surgery

Effect of Ketorolac and Paracetamol on Pain Control after Inguinal Hernia Surgery

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017041033350N1
Enrollment
74
Registered
2017-05-04
Start date
2017-05-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inguinal hernia surgery. inguinal hernia

Interventions

Intervention 1: First intervention group: Injection of Paracetamol (15 mg/ kg every 6 hours, maximal dosage of 60 mg/ kg, daily) one hour after Fentanyl injection. Intervention 2: Second intervention
Treatment - Drugs
First intervention group: Injection of Paracetamol (15 mg/ kg every 6 hours, maximal dosage of 60 mg/ kg, daily) one hour after Fentanyl injection.
Second intervention group: injection of Ketorolac (maximal dosage of 120 mg, daily) one hour after Fentanyl injection.

Sponsors

Vice chancellor for research, Golestan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: age between 20 to 50 years; American Society of Anesthesiologists (ASA) physical status classification system I and II; without chronic and psychologic diseases; no addiction to substance; Under general anesthesia and inducing anesthesia by Fentanyl (1 mcg/ kg), Sodium Thiopental (5 mg/ kg), and Atracurium (0.5 mg/ kg) and maintain it by nitrous oxide (N2O) and Izoflurane; and filling the informed consent form. Exclusion Criteria: needing to administration of extra dosage of drug, another drug; or alternative therapy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain after inguinal hernia surgery. Timepoint: 6 hours after injection of Paracetamol and Ketorolac during time period of 1 hour, every half an hour for 2 hours, and every one hour for 3 hours. Method of measurement: Visual Analogue Scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ali Mahmoud Janlou

Golestan University of Medical Sciences

mahmoud.janlou@goums.ac.ir+98 17 3235 4936

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026