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Evaluation of Rheum ribes L. aqueous extract effect on depression

Evaluation of Rheum ribes L. aqueous extract effect on depression in type2 diabetic patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017041018828N3
Enrollment
54
Registered
2017-04-24
Start date
2017-04-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabete. Diabetes mellitus

Interventions

Intervention 1: The intervention group received required medications and 1200 mg aqueous extract of rhubarb daily for six weeks. Intervention 2: In the control group patients received required medicat
Treatment - Drugs
Placebo
The intervention group received required medications and 1200 mg aqueous extract of rhubarb daily for six weeks.
In the control group patients received required medications and placebo

Sponsors

Vice Chancellor for research of Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: aged 40 to 70 years; with at least 2 years of being diabetes patient; HbA1c <10% exclusion criteria: suffering from other mental diseases under treatment; chronic disease (heart failure, cancer,chronic kidney and chronic liver disease); hospitalized patients with depression ; allergy to Rheum ribes L. aqueous

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Depression. Timepoint: Before the intervention, The end of the fourth week, The end of the Sixth week. Method of measurement: Hamilton Rating Scale for Depression.

Secondary

MeasureTime frame
HbA1C. Timepoint: Before the intervention, After intervention. Method of measurement: Blood Test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlimohamad Ranjbar Jamal abadi

Yazd University of Medical Sciences

amranjbar@razi.tums.ac.ir+382 03865

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026