The effect of intravenous Propofol, Dexamethasone and Ondansetron in preventing nausea and vomiting after cesarean section

Comparison of the prophylactic effect of intravenous Propofol, Dexamethasone and Ondansetron on post operative nausea and vomiting in elective cesarean section under spinal anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170408033280N3

Enrollment

120

Registered

2020-12-12

Start date

2019-07-23

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and vomiting after cesarean section. Nausea and vomiting

Interventions

Intervention 1: Intervention group: group 1: Received 0.05 Mg/kg of Ondansetron from Kaspian-Farma company ( Iran country) after the fetus leaves and umbilical cord clamp by the surgeon. Intervention

Eligibility

Sex/Gender

Female

Age

15 Years to 35 Years

Inclusion criteria

Inclusion criteria: Pregnant women under cesarean section Age group 15-35 years old American Society of Anesthesiologists classification system I and II (ASA II and ASA II)

Exclusion criteria

Exclusion criteria: Having a history of anti depression drugs consumption Gastrointestinal disorders Motion sickness Weight >100 Kg Having a history of other surgeries Patients with preeclampsia and eclampsia during pregnancy Taking anti-nausea and vomiting medications 24 hours before cesarean section

Design outcomes

Primary

Measure	Time frame
Nausea. Timepoint: Recovery and six hours after surgery. Method of measurement: Asking the patient.;Vomoting. Timepoint: Recovery and six hours after surgery. Method of measurement: Push out stomach contents from the mouth.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ebrahim Hassani

Oroumia University of Medical Sciences

ehassani@umsu.ac.ir+98 44 3198 8293

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026