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Comparison of The effect between two dose (800 µg/day & 400 µg/6) of vaginal misoprostol in the termination of first-trimester pregnancy: a double-blinded randomized trial

Comparison of The effect between two dose (800 µg/day & 400 µg/6) of vaginal misoprostol in the termination of first-trimester pregnancy: a double-blinded randomized trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017040633255N1
Enrollment
90
Registered
2017-06-25
Start date
2015-03-29
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

need to medical abortion due to maternal indications or missed abortion and blighted ovum. Medical abortion : incomplete, complicated by delayed or excessive haemorrhage

Interventions

Intervention 1: Intervention group: patients receiving vaginal misoprostol 400 µg every 6 hours up to three days. Intervention 2: control group: the other group is patients receiving vaginal misoprost
Treatment - Drugs
Intervention group: patients receiving vaginal misoprostol 400 µg every 6 hours up to three days
control group: the other group is patients receiving vaginal misoprostol 800 µg daily up to three days

Sponsors

vice chancellor for research of Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
12 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion Criteria: singleton pregnancy; indication for pregnancy termination due to either fetal or maternal causes and gestational age lower than 96 days; no previous misoprostol consuming. exclusion criteria: any sign or symptom of threatened; spontaneous abortion before therapy such as bleeding; any degree of dilatation in cervix or uterine regular contractions before drug administration.

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

MeasureTime frame
Persistent Bleeding. Timepoint: once. Method of measurement: observed by obstetricans.

Primary

MeasureTime frame
Complete abortion without needing to a surgery. Timepoint: once. Method of measurement: observed by the obstetrician.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Donya Khosravi

Imam Hossein Hospital

donyakhosravi@sbmu.ac.ir+98 912 497 1038

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026