The effect of adding dexmedetomidine to lidocaine on nerve block.

Evaluation the effect of adding dexmedetomidine to lidocaine to improve quality of block and reduce the pain in patients who are candidates for fracture surgeries by supraclavicular block procedure under ultrasonic-guide.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017040433210N1

Enrollment

Registered

2017-06-25

Start date

2017-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral nerve block.

Interventions

Intervention 1: Control group: Injection of 30 milliliter solution containing isotonic Normal Saline plus 1 percent Lidocaine under ultrasound guidance after sensory and motor block beginning. Interve

Treatment - Drugs

Control group: Injection of 30 milliliter solution containing isotonic Normal Saline plus 1 percent Lidocaine under ultrasound guidance after sensory and motor block beginning.

Intervention group: Injection of 30 milliliter solution containing 1 mcg per kg dexmedetomidine plus 1 percent Lidocaine under ultrasound guidance after sensory and motor block beginning.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients at the age of 18-60 years with ASA physical status I or II who are candidate for forearm surgery. Exclusion criteria : History of cardiovascular and liver diseases; Sensitivity to drugs used in study; Use alfa-2 adrenergic and/or analgesic before the surgery; Patients with neurological and/or psychological disorders.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Onset of sensory block. Timepoint: 5-10-15 -30 minute intervals after injection. Method of measurement: Physical Examination by Physician (Pinprick test).;Onset of motor block. Timepoint: 5, 10, 15 and 30 minutes after injection. Method of measurement: Physical Examination by Physician (modified bromage scale).;Duration of sensory block. Timepoint: Untile patients analgesic request. Method of measurement: Physical Examination by Physician.;Duration of motor block. Timepoint: Untile start movement around median, radial, and ulnar nerves. Method of measurement: Physical Examination by Physician.;The time of first Analgesic Request. Timepoint: One hour intervals untile first 24 hours. Method of measurement: Patient's file.;Analgesic received in 24 hours. Timepoint: 24 hours after surgery. Method of measurement: Patient's documents.	—

Measure

Time frame

Onset of sensory block. Timepoint: 5-10-15 -30 minute intervals after injection. Method of measurement: Physical Examination by Physician (Pinprick test).;Onset of motor block. Timepoint: 5, 10, 15 and 30 minutes after injection. Method of measurement: Physical Examination by Physician (modified bromage scale).;Duration of sensory block. Timepoint: Untile patients analgesic request. Method of measurement: Physical Examination by Physician.;Duration of motor block. Timepoint: Untile start movement around median, radial, and ulnar nerves. Method of measurement: Physical Examination by Physician.;The time of first Analgesic Request. Timepoint: One hour intervals untile first 24 hours. Method of measurement: Patient's file.;Analgesic received in 24 hours. Timepoint: 24 hours after surgery. Method of measurement: Patient's documents.

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Secondary

Measure	Time frame
Heart Rate per minute. Timepoint: Before block (base line) then every 5 minutes after block, then every 5 minutes after starting surgery till end of surgery and then every 15 minute till Departure time from recovery. Method of measurement: Cardiac Monitoring Device.;Arterial Oxygen Saturation. Timepoint: Before block (base line) then every 5 minutes after block, then every 5 minutes after starting surgery till end of surgery and then every 15 minute till Departure time from recovery. Method of measurement: Continious Pulse Oximetry.;Mean Arterial Pressure. Timepoint: Before block (base line) then every 5 minutes after block, then every 5 minutes after starting surgery till end of surgery and then every 15 minute till Departure time from recovery. Method of measurement: By non-invasive Manometer device(millimeter Hg).	—

Measure

Time frame

Heart Rate per minute. Timepoint: Before block (base line) then every 5 minutes after block, then every 5 minutes after starting surgery till end of surgery and then every 15 minute till Departure time from recovery. Method of measurement: Cardiac Monitoring Device.;Arterial Oxygen Saturation. Timepoint: Before block (base line) then every 5 minutes after block, then every 5 minutes after starting surgery till end of surgery and then every 15 minute till Departure time from recovery. Method of measurement: Continious Pulse Oximetry.;Mean Arterial Pressure. Timepoint: Before block (base line) then every 5 minutes after block, then every 5 minutes after starting surgery till end of surgery and then every 15 minute till Departure time from recovery. Method of measurement: By non-invasive Manometer device(millimeter Hg).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Amir Hosein Baniahmad

Ahvaz Jundishapur University of Medical Sciences

baniahmad.a@ajums.ac.ir; ahbaniahmad@gmail.com+98 61 3222 0168

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026