fatty liver. (Nonalcoholic steatohepatitis (NASH
Conditions
Interventions
Intervention 1: Metformin, 500 mg, twice a day, for three months. Intervention 2: Vitamin E 400 IU, once daily, for three months. Intervention 3: Artichoke herbal preparation containing 320 mg three t
Treatment - Drugs
Metformin, 500 mg, twice a day, for three months
Vitamin E 400 IU, once daily, for three months
Artichoke herbal preparation containing 320 mg three times a day, for three days
Sponsors
Vice Chancellor for Research and Technology Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria included: 1- Confirmed fatty liver disease using ultrasound, 2- High liver enzymes (ALT, AST),3-Aged between 18 and 70 years,4-The first visit is to treat fatty liver disease.Exclusion criteria included were: 1.Alcoholism, 2 Have a history of diabetes, cardiovascular disease, various cancers, diseases of the liver (hepatitis, liver failure, cirrhosis), kidney failure and gastrointestinal bleeding wound, 3. Being pregnant and breastfeeding infant,4-Not wanting to continue the study,5- BMI> 35,6.Have any allergies to medications,7-The use of any supplement (including herbal supplements) and vitamins such as vitamin A, H, B (2,6,12 and complex), C, D).
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver enzymes. Timepoint: 3 months after the intervention. Method of measurement: Using the Spectrophotometer IU/L.;LDL Cholesterol. Timepoint: Three months after the intervention. Method of measurement: using a spectrophotometer mg / dl.;HDL Cholesterol. Timepoint: Three months after the intervention. Method of measurement: using a spectrophotometer mg/dl.;Triglyceride. Timepoint: Three months after the intervention. Method of measurement: using a spectrophotometer mg / dl.;Fasting sugar. Timepoint: Three months after the intervention. Method of measurement: using a spectrophotometer mg / dl.;Body mass index. Timepoint: Three months after the intervention. Method of measurement: Kg/m2. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood presure. Timepoint: Introduction to the study and three months after the intervention. Method of measurement: Using the mercury pressure gauge.;The number of blood cells. Timepoint: Introduction to the study and three months after the intervention. Method of measurement: Using the auto blood cell counting analyzer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactmohammad bagher majnooni
Kermanshah University of Medical Sciences
Outcome results
None listed