Effects of propolis on diabetic foot ulcer

Compare the effects of oral propolis with topical propolis on diabetic foot ulcer

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017040419669N3

Enrollment

Registered

2017-04-15

Start date

2017-04-04

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic food ulcers. Ulcer of lower limb, not elsewhere classified

Interventions

Intervention 1: Control group : Rinse with saline daily. Intervention 2: Intervention group 3: 1500 mg Propolis ointment for topical use on the ulcer and 1500 mg Propolis capsules (three 500 mg capsu

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with diabetic foot ulcers grade 1 and 2 Willingness to cooperate

Exclusion criteria

Exclusion criteria: Patients with wounds functions deep grade and step higher than 1 and 2 Sensitivity to topical formulation

Design outcomes

Primary

Measure	Time frame
Area of diabetic foot ulcers. Timepoint: The beginning and End of the study. Method of measurement: With AutoCAD software.;Average leukocytes in diabetic foot ulcers. Timepoint: The beginning and End of the study. Method of measurement: The sampling.;The number of pathogenic bacteria. Timepoint: The beginning and End of the study. Method of measurement: The Sampling and culture.;Total Antioxidant Capacity. Timepoint: The beginning and End of the study. Method of measurement: Eliza kit.;?serum Malondialdehyde. Timepoint: The beginning and End of the study. Method of measurement: Eliza kit.	—

Measure

Time frame

Area of diabetic foot ulcers. Timepoint: The beginning and End of the study. Method of measurement: With AutoCAD software.;Average leukocytes in diabetic foot ulcers. Timepoint: The beginning and End of the study. Method of measurement: The sampling.;The number of pathogenic bacteria. Timepoint: The beginning and End of the study. Method of measurement: The Sampling and culture.;Total Antioxidant Capacity. Timepoint: The beginning and End of the study. Method of measurement: Eliza kit.;?serum Malondialdehyde. Timepoint: The beginning and End of the study. Method of measurement: Eliza kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hossein Khadem Haghighian

Qazvin University of Medical Sciences

khademnut@yahoo.com+98 28 3732 7650

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026