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Evaluation of Plantago?Marigold and honey (traditional medicine product) with placebo on dermatitis caused by radiotherapy in cancer patients

Evaluation of Plantago?Marigold and honey (traditional medicine product) with placebo on dermatitis caused by radiotherapy in cancer patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170404033202N11
Enrollment
84
Registered
2022-07-29
Start date
2023-02-20
Completion date
Unknown
Last updated
2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

radiation therapy-induced dermatitis. Radiodermatitis, unspecified

Interventions

Intervention 1: Intervention group: Intervention group: The medicine of the intervention group is hydrogel, which includes marigold, marshmallow, and honey. This topical skin hydrogel will be made by

Sponsors

Sabzevar University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: Consent to participate in the study Mental and intellectual health Radiotherapy candidate Staying in Bezvar and suburbs (all meetings should be held in Bezvar) Age range 45-70 years Absence of underlying chronic disease: dermatology, lupus, active scleroderma, underlying allergy, diabetes, and chronic kidney disease No smoking, drugs and alcohol

Exclusion criteria

Exclusion criteria: People who have changed their place of residence since the middle of the study Do not agree to continue participating in the project from the middle of the study suffer severe complications from radiotherapy. Changing the patient's treatment method from the middle of the treatment process Failure to use plan drugs have allergies to study drugs

Design outcomes

Primary

MeasureTime frame
Dermatitis. Timepoint: Day 0 (day of starting radiation therapy and start of intervention) and days 7-14-21 after the treatment and one month after the end of the treatment to check acute dermatitis and 3 months after the end of treatment to check sub-acute dermatitis. Method of measurement: CTCAE v5.0.

Secondary

MeasureTime frame
Itching. Timepoint: (From start of intervention) to day 7-21-28 (from the start of radiotherapy once a week). Method of measurement: self expression.;Erythema. Timepoint: (From start of intervention) to day 7-21-28 (from the start of radiotherapy once a week). Method of measurement: view.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Asadi

Sabzevar University of Medical Sciences

a.asadi.mm.1384@gmail.com+98 51 4422 9081

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026