Comparison of the cold normal saline, lidocaine and metoclopramide and the combination of lidocaine and cold normal saline on pain caused by propofol injection

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170404033202N10

Enrollment

120

Registered

2022-03-23

Start date

2021-11-22

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reduction of pain caused by propofol in anesthesia.

Interventions

Intervention 1: Intervention group 1: The case group consisting of four groups including the first group will inject 10 ml of 0.5% lidocaine at room temperature. The tourniquet is emptied 15 seconds a

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Need for general anesthesia with propofol injection with consent to participate in evaluation between 18 and 60 years old ASA class 1 and 2

Exclusion criteria

Exclusion criteria: Reluctance to studyPatients Patients under 20 years and over 60 years Patients with ASA grade equal to or greater than 3 Patients with advanced heart and lung problems Sensitivity to any of the drugs used in the study

Design outcomes

Primary

Measure	Time frame
Reduction of pain caused by propofol injection after drug injection. Timepoint: Pain rate at 0, 15 and 30 minutes after propofol injection. Method of measurement: Based on VAS from zero to 10.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Nematshahi

Sabzevar University of Medical Sciences

9151737407mn@gmail.com098 51 44229081

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026