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Effect of flaxseed in patients with heart disease

Effect of flaxseed consumption on inflammation and vascular endothelial function markers in coronary artery disease patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017040328742N2
Enrollment
60
Registered
2017-06-13
Start date
2017-04-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary heart disease. Atherosclerotic heart disease

Interventions

Intervention 1: Control: Daily consumption of one capsule containing 1 gr wheat fiber for 3 months. Intervention 2: Intervention: Daily consumption of 30 gr flaxseed for 3 months.
Lifestyle
Control: Daily consumption of one capsule containing 1 gr wheat fiber for 3 months
Intervention: Daily consumption of 30 gr flaxseed for 3 months

Sponsors

Vice chancellor for research, Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 1) coronary artery disease patients (more than 50% blockage in coronary arteries) needed angioplasty with stent 2) willing to participation in the study ?Exclusion Criteria: 1) cigarette Smoking 2) continuous consumption of any antioxidant supplement such as vitamin E, vitamin C and Selenium in last month 3) consumption of flaxseed or any omega-3 supplement at the beginning of the study 4) ?advanced renal disease 5) unwillingness to continuance 6) any change in disease treatment plan such as change in type and dose of lipid lowering drugs or surgical operation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Flow Mediated Dilatation (FMD). Timepoint: Baseline and the end of the study. Method of measurement: Ultrasound Sonography.

Secondary

MeasureTime frame
Blood inflammatory cytokines. Timepoint: At baseline and the end of the study. Method of measurement: ELISA.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNafiseh Khandouzi

Faculty of Nutrition Sciences, Shahid Beheshti University of Medical Sciences

khandozi_n@yahoo.com; n-khandouzi@sbmu.ac.ir+98 21 2207 7424

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026