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Comparison of intrauterine injection effects of PRP (platelet-rich plasma) and Hams F10 on the pregnancy outcome in recurrent implantation failure of infertile women after transferring unfrozen embryo

Comparison of intrauterine injection effects of PRP (platelet-rich plasma) and Hams F10 on the pregnancy outcome in recurrent implantation failure of infertile women after transferring unfrozen embryo

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017033133179N1
Enrollment
46
Registered
2017-04-08
Start date
2016-10-29
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intrauterine injection of 0.5 to 1 ml platelet-rich plasma 24 to 36 hours before implantation. Intervention 2: Intrauterine injection of 0.5 to 1 ml Hams F10 24 to 36 hours before impl
Treatment - Drugs
Intrauterine injection of 0.5 to 1 ml platelet-rich plasma 24 to 36 hours before implantation
Intrauterine injection of 0.5 to 1 ml Hams F10 24 to 36 hours before implantation

Sponsors

Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 42 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age of 20 to 42 years; implantation failure for at least 3 times. Exclusion criteria: pregnancy contraindication; weak response to gonadotropin; presence of any type of chronic disease such as anemia or endocrine disorders or renal failure.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Assessing pregnancy. Timepoint: 2 weeks after intervention. Method of measurement: with ßhCG.—

Secondary

MeasureTime frame
Assessing pregnancy. Timepoint: 4 weeks after intervention. Method of measurement: with ultrasonography.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Nasrin Azami Fard

Hamadan University of Medical Sciences

nazami51@gmail.com+98 81 3821 9905

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026