The effect of exercise training on women with multiple sclerosis

The effect of 12-weeks combined exercise training on body composition, disability scale, and NGF, BDNF, and VDBP serum concentrations in women with multiple sclerosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017032633146N1

Enrollment

Registered

2017-08-11

Start date

2015-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis. Multiple sclerosis

Interventions

Intervention 1: Intervention group: combined exercise training included aerobic and resistance exercises, three sessions per week (two sessions of aerobic training and one session of resistance traini

Rehabilitation

Intervention group: combined exercise training included aerobic and resistance exercises, three sessions per week (two sessions of aerobic training and one session of resistance training), lasting 12

Control group: had received no exercises and did their normal activities

Eligibility

Sex/Gender

Female

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Inclusion criteria: EDSS score of 2 to 5 (approved by neurologist through MS diagnostic tests including MRI or CT scan and functional tests for balance, strength, walking ability, and visual and tactile senses); women aged between 20 and 50 years; regular menstrual cycle, donot presence of any other acute or chronic diseases; not participating in any regular exercise training. Exclusion criteria: Did not have one of the condition of entry

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Nerve growth factor(NGF). Timepoint: Before and after training. Method of measurement: ELISA Kit.;Brain-derived neurotrophic factor(BDNF). Timepoint: Before and after training. Method of measurement: ELISA Kit.;Vitamin D-binding protein(VDBP). Timepoint: Before and after training. Method of measurement: ELISA Kit.;Disability status scale. Timepoint: Before and after training. Method of measurement: Questionnaire.	—

Measure

Time frame

Nerve growth factor(NGF). Timepoint: Before and after training. Method of measurement: ELISA Kit.;Brain-derived neurotrophic factor(BDNF). Timepoint: Before and after training. Method of measurement: ELISA Kit.;Vitamin D-binding protein(VDBP). Timepoint: Before and after training. Method of measurement: ELISA Kit.;Disability status scale. Timepoint: Before and after training. Method of measurement: Questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMitra Khademosharie

Razi University

m_khadem_un@yahoo.com+98 51 4465 9021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026