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The effects of Laser and Microneedling combined with phototherapy for treating vitiligo in resistant of hair skin

Assay of the CO2 fractional laser and micro needling plus hair follicle transplantation in the treatment of refractory and stable vitiligo.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017032530808N3
Enrollment
20
Registered
2017-04-24
Start date
2016-01-13
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitiligo. Vitiligo

Interventions

Comparable vitiliginous lesions were selected from both sides of the body. On Day 0, heavily pigmented follicular grafts were harvested from the scalp by follicular unit extraction and transplanted in
Dr. Honle medizinitechnik, GmbH, Germany) three times a week until Day 60±4
phototherapy was restarted on day 71±2. The phototherapeutic dose was increased by 15% at each treatment interval and was completed by Day 100±4 (for a total of 12 weeks of treatment). Clobetasol 45%
Treatment - Surgery
phototherapy was restarted on day 71±2. The phototherapeutic dose was in

Sponsors

Vice chancellor for research, Jahrom University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria included:All patients were dermatologically diagnosed with refractory, palmar-plantar vitiligo exclusion criteria included:hypersensitivity to laser and hair transplantation materials

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Scale of pigmentation improvement of lesion( scale of repigmentation). Timepoint: in Three month ,each month once after intervention. Method of measurement: The scale of repigmentation (increase the amount of pigment in vitiligo patches) will be classified based on percentage of improvement in 4 grades. The ratings are: Scale 0: no repigmentation- Scale 1: Returning pigmentation between 0% to 25% which is mild pigmentation- Scale 2: The return of pigmentation 25% and 50% which is average- Scale 3: Good pigmentation which is between 50% to 75%- Scale 4: the return of pigmentation between 75% and 100% which is considered excellent. Measurements are performed by a physician through examination under a Wood's lamp and photography.

Secondary

MeasureTime frame
Complications due to interventions. Timepoint: 1 week, 4 week, 2 months, 4 months and 6 months after start of treatment. Method of measurement: Every kind of local or generalized complication due to intervention which according to the confirm of dermatologist should be recorded in the questionnaire. These complications are usually redness and irritation at the site of intervention.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNavid Kalani

Jahrom University of Medical Sciences

navidkalani@ymail.com+98 7157414846199

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026