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The nebulized Budezonide (pulmicort) effectiveness in acute adult asthma attack

Comparison of the effectiveness of nebulized Budezonide (pulmicort) versus placebo in the treatment of adult with moderate to severe acute asthma referring to Dr Shariati and Sina hospitals from 2017 to 2018

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170325033132N3
Enrollment
40
Registered
2018-02-18
Start date
2016-03-20
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

asthma. Severe persistent asthma with (acute) exacerbation

Interventions

Intervention 1: Intervention group: patients with acute asthma, nebulized budezonide(pulmicort) will be administered with the dose of 0.5 mg every half an hour up to three dose in additional standard

Sponsors

Astra Zeneca
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age > 18 with signed informed consent letter Patients with acute asthma(moderate to severe)

Exclusion criteria

Exclusion criteria: Unwillingness of patients to participate in the study Patients with COPD Pneumonia Pneumothorax CHF Acute and severe respiratory failure with cyanosis and confusion Loss of consciousness Pregnant patients Smokers Intubated patients and patients with unstable vital signs New case of asthma Hemodynamic instability

Design outcomes

Primary

MeasureTime frame
Improvement of vital sign and clinical symptoms in patients with asthma attack. Timepoint: At the begining of the study(before intervention), 30, 60, 180 minutes after treatment. Method of measurement: physical exam.

Secondary

MeasureTime frame
Relief of acute asthma attack(sign and symptom)from patient and dr "view. Timepoint: During the treatment in emergency center. Method of measurement: by completing questionnaire form, follow up, ask question about the number of readmission rate and length of hospitalization.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmaryam habibi samadi

Tehran University of Medical Sciences

maryamhabibi2011@yahoo.com+98 21 84901

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026