Non celiac gluten sensitivity disorder.
Conditions
Interventions
Intervention 1: Gluten free muffins will given to control group for one week. Intervention 2: Gluten contain muffin (contain about 8gr gluten daily or 160 gr muffin daily) will given to intervention g
Treatment - Other
Gluten free muffins will given to control group for one week.
Gluten contain muffin (contain about 8gr gluten daily or 160 gr muffin daily) will given to intervention group for one week
Sponsors
Researchers
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: In this study, patients aged 18 to 55 years old suffering from dyspepsia resistant to treatment and there was no specific cause for them in initial check and celiac disease and allergic to wheat have been ruled out, non-celiac gluten sensitivity (NCGS) are considered. All of the patients underwent 6 weeks of gluten-free diet. Individuals that have no improvement in symptoms, will excluded from our study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rsolving of intestinal and extraintestinal symptoms. Timepoint: Before the study, at the end of first and third weeks. Method of measurement: Questionnaire of clinical symptoms according to numerical rating scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum anti Anti gliadin IgG level, fecal calprotectin. Timepoint: Before the study, at the end of first and third weeks. Method of measurement: Blood tests (ELISA) and stool tests (ELISA). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Mahdi Fanaeian
Tehran University of Medical Sciences
Outcome results
None listed