Delirium. Delirium, unspecified
Conditions
Interventions
Intervention 1: Intervention group 1 (clonidine): They will receive 100 micrograms clonidine the night before surgery at bedtime and 100 micrograms 90 minutes before surgery. Intervention 2: Intervent
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients undergoing major elective orthopedic surgery Age above 65 years Informed consent for participation
Exclusion criteria
Exclusion criteria: Abbreviated mental test score below 8 Blood pressure lower than 100 millimeters of mercury History of depression that has resulted in hospitalization or use of psychiatric drugs Dementia History of head trauma causing hematoma or dementia History of tumor and cerebral infarction History of common disorders of the glands such as hyperthyroidism and hypothyroidism Chronic metabolic disorders History of head and neck radiotherapy History of poisoning with heavy metals and carbon monoxide Alcohol consumption for more than a year Chronic liver and kidney disease Presence of chronic infectious diseases Consumption of psychiatric and hypnotic drugs on a regular basis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delirium. Timepoint: 24, 48, and 72 hours after syrgery. Method of measurement: abbreviated mental test and mini-mental state examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Amirhosain Ebrahimi
Birjand University of Medical Sciences
Outcome results
None listed