Effect of vitamin D on the improvement of infants and children with congenital heart disease

Comparing the effects of vitamin D and placebo on the treatment course of neonates, infants, and children with congenital heart disease following corrective heart surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170316033099N6

Enrollment

Registered

2019-02-09

Start date

2018-12-22

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital heart disease. Congenital malformation of heart, unspecified

Interventions

Intervention 1: Intervention group (Vitamin D): Before surgery, 300,000 units of vitamin D will be given orally in the form of six 50,000 unit pearls soaked in water. Intervention 2: Control group (p

Eligibility

Sex/Gender

All

Age

1 Days to 18 Years

Inclusion criteria

Inclusion criteria: Suffering from congenital heart disease Risk adjustment for congenital heart surgery score below 5 Age below or equal to 18 years Serum vitamin D level below or equal to 150 nanograms per milliliter Consent from parent or legal guardian to participate in the study The patient being candidate for open heart surgery

Exclusion criteria

Exclusion criteria: Being treated with steroidal drugs Vitamin D contraindications Application of cardio-respiratory support device Contraindications for oral medication Active cardiopulmonary resuscitation

Design outcomes

Primary

Measure	Time frame
Vasoactive-Inotrope Score. Timepoint: 24 and 48 hours postoperatively. Method of measurement: Vasoactive-Inotrope Score calculation formula.;Vasoactive-Inotrope Score. Timepoint: 24 and 48 hours postoperatively. Method of measurement: Inotrope Score calculation formula.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Emad Askari Jafarabadi

Birjand University of Medical Sciences

dr.askary@hotmail.com+98 56 3239 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026