major orthopedic surgery. Unspecified complication of internal orthopaedic prosthetic device, implant and graft
Conditions
Interventions
Intervention 1: Intervention group 1 (General anesthesia): One day before the operation, the serum levels of vitamin D, cystatin C, and CRP will be measured, and the mini mental state examination will
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients undergoing elective major orthopedic surgeries in lower extremities and thighs Age over 40 years Referral to Imam Reza Hospital and Razi Hospital in Birjand Completion of informed consent form
Exclusion criteria
Exclusion criteria: Anxiety and psychiatric disorders before operation Alcohol consumption and psychotropic drugs abuse Drug addiction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive dysfunction. Timepoint: One day before surgery and one week after surgery. Method of measurement: mini mental state examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum vitamin D level. Timepoint: One day before and one week after surgery. Method of measurement: DiaSorin laboratory kit.;Serum cystatin C level. Timepoint: One day before and one week after surgery. Method of measurement: Nephstar laboratory kit.;Serum CRP level. Timepoint: One day before and one week after surgery. Method of measurement: Nephstar laboratory kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Vahid Afkhamifard
Birjand University of Medical Sciences
Outcome results
None listed