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An Investigation of keto-vi effect as an adjuvant therapy in glioblastoma patients

An Investigation on the keto-vi based metabolic therapy on mTOR signaling pathway in glioblastoma patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170315033086N9
Enrollment
15
Registered
2021-03-02
Start date
2019-11-21
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioblastoma. Neoplasm of uncertain behavior of brain, unspecified

Interventions

Intervention 1: Intervention group: Intervention group: Receiving ketogenic diet after an introduction meeting, using Keto-Vi Medical Food (Caprylate+ Caprate + Natural flavor), manufactured by Kondor

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to No maximum

Inclusion criteria

Inclusion criteria: Age more than 16 BMI more than 20 performance status equal or less than 2 Glioma grade 4 Surgical gross resection of the tumor Treating with temozolomide early diagnosed

Exclusion criteria

Exclusion criteria: Any previous consumption of Caprylate and Caprate fats Kidney, liver and bladder failure Nutritional disorder (Anorexia, Bulimia, Binge eating disorder) Any metabolic disorder Diabetic person who take medication taking weight loss pills Pregnancy and lactation Performance status equal or more than 3 Patients with problems such as deficiencies in pyruvate carboxylase, porphyria and hereditary diseases of lipid metabolism disorder

Design outcomes

Primary

MeasureTime frame
Quality of life. Timepoint: Baseline, 45 days and four months after keto-vi usage. Method of measurement: EORTC QLQ C30 and QLQ BN 20 questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeed Karima

Shahid Beheshti University of Medical Sciences

karima@sbmu.ac.ir+98 21 2387 2570

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026