Study the effect of CAPRIDIN in the metabolic treatment of drug-resistant epilepsy

Study the effect of metabolic treatment based on a diet containing CAPRIDIN on adenosine regulatory pathways in brain tissue of patients with drug-resistant epilepsy

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170315033086N11

Enrollment

Registered

2023-05-31

Start date

2023-06-05

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug-resistant temporal lobe epilepsy. Localization-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures

Interventions

Intervention 1: Intervention group: patients who take 30 cc of CAPRIDIN daily with food, in addition to the standard treatment of epilepsy, for an average of two months. Capridin is a product of Healt

Eligibility

Sex/Gender

All

Age

15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with drug-resistant temporal lobe epilepsy Taking up to 3 or more standard anticonvulsants Having at least 3 seizures per month.

Exclusion criteria

Exclusion criteria: Failure to adhere to dietary guidelines. Metabolic syndrome Pregnancy

Design outcomes

Primary

Measure	Time frame
Expression level of ecto-5-nucleotidase (CD73) in the patients brain tissue. Timepoint: Two months after taking CAPRIDIN and then brain tissue sampling after surgery. Method of measurement: Using Real-Time PCR and Western blot techniques.;Expression level of adenosine kinase in the patients brain tissue. Timepoint: Two months after taking CAPRIDIN and then brain tissue sampling after surgery. Method of measurement: Using Real-Time PCR and Western blot techniques.	—

Measure

Time frame

Expression level of ecto-5-nucleotidase (CD73) in the patients brain tissue. Timepoint: Two months after taking CAPRIDIN and then brain tissue sampling after surgery. Method of measurement: Using Real-Time PCR and Western blot techniques.;Expression level of adenosine kinase in the patients brain tissue. Timepoint: Two months after taking CAPRIDIN and then brain tissue sampling after surgery. Method of measurement: Using Real-Time PCR and Western blot techniques.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeed Karima

Shahid Beheshti University of Medical Sciences

karima@sbmu.ac.ir+98 21 2387 2570

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026