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Effect of Nigella Sativa capsules on preparation of endometrium for frozen embryo transfer cycles

Effect of Nigella Sativa capsules in order to prepare endometrium for frozen embryo transfer

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170315033085N5
Enrollment
116
Registered
2021-03-23
Start date
2021-04-09
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Decreased or lack of fertility in a woman of childbearing age. Female infertility, unspecified

Interventions

Intervention 1: Intervention group: In this group, patients are prescribed one Nigella Sativa capsule each night in the first 7 days of menstruation and then one in the morning and one at night until

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 42 Years

Inclusion criteria

Inclusion criteria: Women between 20 and 42 years old with a frozen fetus who are candidate for embryo transfer

Exclusion criteria

Exclusion criteria: Allergy to herbal medicines and specifically Nigella Sativa

Design outcomes

Primary

MeasureTime frame
Endometrial thickness. Timepoint: Third, tenth, twelfth, and fourteenth day of the cycle. Method of measurement: Transvaginal ultrasound.;Fertility rate. Timepoint: Two weeks after embryo transfer. Method of measurement: Beta HCG test.;Implantation rate. Timepoint: 35 days after embryo transfer and 7 days after a positive result on pregnancy test. Method of measurement: Transvaginal ultrasound.;Subclinical pregnancy. Timepoint: 14 days after embryo transfer. Method of measurement: Beta HCG test.;Clinical pregnancy. Timepoint: 42 days after embryo transfer. Method of measurement: Transvaginal ultrasound.

Secondary

MeasureTime frame
Live birth rate. Timepoint: after delivery. Method of measurement: live fetus delivery after 28 weeks of gestational age.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Malihe Afiat

Mashhad University of Medical Sciences

afiatm@mums.ac.ir+98 51 3802 2406

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026