letrozole and Dexametazon effect in Poly cystic ovarian syndrome patients

The Effect of Letrozole and Dexamethasone on pregnancy outcome in Poly cystic ovarian syndrome patients candidate for intra uterine insemination: Randomized Clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170315033085N4

Enrollment

106

Registered

2018-07-29

Start date

2013-02-03

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polycystic ovarian syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Control group: group A received letrozole tablet ( abouraihan , Iran ) 5 mg from day 3 of menstrual cycle for 5 days .They were monitored hormonal and Sonographical on day 3 and day 1

Eligibility

Sex/Gender

Female

Age

20 Years to 35 Years

Inclusion criteria

Inclusion criteria: AGE: 25-35 years at least one patent Fallopian tube normal sperm analysis of spouse presence of poly-cystic ovarian syndrome

Exclusion criteria

Exclusion criteria: Smoking underlying disease ( heart, kidney, liver or Endocrine)

Design outcomes

Primary

Measure	Time frame
Luteinizing hormone. Timepoint: Third and 12th day of menstrual cycle. Method of measurement: laboratory Test.;Testestron. Timepoint: Third and 12th day of menstrual cycle. Method of measurement: laboratory Test.;Anderestandion. Timepoint: Third and 12th day of menstrual cycle. Method of measurement: laboratory Test.;Esteradiol. Timepoint: Third and 12th day of menstrual cycle. Method of measurement: laboratory Test.;Pregnancy. Timepoint: 14 days after Intrauterine insemination. Method of measurement: laboratory Test, pregnancy test.	—

Measure

Time frame

Luteinizing hormone. Timepoint: Third and 12th day of menstrual cycle. Method of measurement: laboratory Test.;Testestron. Timepoint: Third and 12th day of menstrual cycle. Method of measurement: laboratory Test.;Anderestandion. Timepoint: Third and 12th day of menstrual cycle. Method of measurement: laboratory Test.;Esteradiol. Timepoint: Third and 12th day of menstrual cycle. Method of measurement: laboratory Test.;Pregnancy. Timepoint: 14 days after Intrauterine insemination. Method of measurement: laboratory Test, pregnancy test.

—

Secondary

Measure	Time frame
Dominant follicles. Timepoint: 12th day of Menestural cycle. Method of measurement: vaginal Sonography.;Endometrium thickness. Timepoint: 12th day of Menestural cycle. Method of measurement: vaginal Sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMalihe Afiat

Mashhad University of Medical Sciences

Afiatm@mums.ac.ir+98 51 3802 2608

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026