Comparison of changes in blood pressure and heart rate in patients undergoing orthopedic surgery of the lower limbs in two anesthesia method.

comparsion of hemodynamic changes in elderly patients undergoing orthopedic surgery of the lower limbs in tow ways subarachnoid bupivacain and subarachnoid meperidin

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2017031414333N71

Enrollment

Registered

2017-04-06

Start date

2017-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture of Lower Limb. Fracture of lower limb, level unspecified

Interventions

Intervention 1: In the first group anesthesia with bupivacaine spinal, the patient is placed in a sitting position and by spinal needle number 15-25,12.5-24 mg of bupivacaine half percent (0.5 %) (2.5

Treatment - Drugs

In the first group anesthesia with bupivacaine spinal, the patient is placed in a sitting position and by spinal needle number 15-25,12.5-24 mg of bupivacaine half percent (0.5 %) (2.5 ml) in subarach

In the second group the patient is placed in a sitting position and by spinal needle number 24-25 pethidine with the dose of 1 mg plus 2 ml csf in the subarachnoid space (between the vertebrae l2-l3 a

Eligibility

Sex/Gender

All

Age

60 Years to 100 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age over 60 years; Patients of class 1 and 2 ASA-PS. Exclusion criteria: Patients who consume narcotic drugs and psychotropic substances; patients generally have a contraindication to spinal procedures; Patients who experience severe pain during the surgery and have to use general anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Itching. Timepoint: First, during, and after the end of the study. Method of measurement: Based on patient interview.;Nausea and vomiting. Timepoint: First, during, and after the end of the study. Method of measurement: Based on patient interview.;Urinary retention. Timepoint: First, during, and after the end of the study. Method of measurement: Based on patient interview.;Respiratory depression. Timepoint: First, during, and after the end of the study. Method of measurement: Based on the questions of the patient and a doctor diagnoses.;Duration of analgesia. Timepoint: The first, second, third, fourth, fifth, sixth hours after the start of the study. Method of measurement: Based on the questions of the patient and a doctor diagnoses.;Hemodynamic changes. Timepoint: First, during, and after the end of the study. Method of measurement: Based on manometer and monitor.	—

Measure

Time frame

Itching. Timepoint: First, during, and after the end of the study. Method of measurement: Based on patient interview.;Nausea and vomiting. Timepoint: First, during, and after the end of the study. Method of measurement: Based on patient interview.;Urinary retention. Timepoint: First, during, and after the end of the study. Method of measurement: Based on patient interview.;Respiratory depression. Timepoint: First, during, and after the end of the study. Method of measurement: Based on the questions of the patient and a doctor diagnoses.;Duration of analgesia. Timepoint: The first, second, third, fourth, fifth, sixth hours after the start of the study. Method of measurement: Based on the questions of the patient and a doctor diagnoses.;Hemodynamic changes. Timepoint: First, during, and after the end of the study. Method of measurement: Based on manometer and monitor.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hamzeh Hasani

Kermanshah University of Medical Sciences

hhasani95@gmail.com00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026