Investigating the effect of aminophylline on the recovery time of patients after hysterectomy. Complications of anesthesia during labor and delivery
Conditions
Interventions
Intervention 1: Intervention group: After uterus removal by the surgeon, patients in the intervention group will receive 3 milligrams per kilogram of intravenous aminophylline (manufactured by Caspian
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologists (ASA) I,II Candidate for hysterectomy under general anesthesia in Alzahra hospital Women aged 30 to 70
Exclusion criteria
Exclusion criteria: Hysterectomy due to malignancy Any history of allergy to aminophylline or drug components Any dysfunction of the liver, including liver cirrhosis, fatty liver, etc smokers People who have recently received or are taking cimetidine, ciprofloxacin, and macrolides such as erythromycin and clarithromycin History of any type of arrhythmia or neurological disorder such as epilepsy Patient dissatisfaction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Emergence from anesthesia. Timepoint: From the time of discontinuing administration of anesthetic drugs to the time of patient's eyes getting open after calling her/his name. Method of measurement: Time measurement.;Extubation time. Timepoint: From the time of discontinuing administration of anesthetic drugs to the time of removing the endotracheal tube. Method of measurement: Time measurement.;Recovery time. Timepoint: From the time of discontinuing administration of anesthetic drugs to the time of transferring the patient to the ward. Method of measurement: Time measurement. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial blood pressure (MAP). Timepoint: Before administration of aminophylline and normal saline and then every 5 minutes until transferring to recovery, then every 15 minutes during recovery. Method of measurement: Blood pressure measurement with mercury sphygmomanometer.;Heart rate. Timepoint: Before administration of aminophylline and normal saline and then every 5 minutes until transferring to recovery, then every 15 minutes during recovery. Method of measurement: Heart rate monitor. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Gelareh Biazar
Rasht University of Medical Sciences
Outcome results
None listed