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effectiveness of licorice to improve aphthae

Evaluate the effectiveness of licorice extract to improve recurrent aphthous stomatitis (RAS)

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017031333046N1
Enrollment
42
Registered
2017-04-16
Start date
2016-12-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent aphthous ulcers. recurrent aphthous stomatitis

Interventions

Intervention 1: Mucosal Adhesive 3 times a day for seven days. Intervention 2: Mucous adhesive containing licorice extract three times a day for seven days.
Placebo
Treatment - Drugs
Mucosal Adhesive 3 times a day for seven days
Mucous adhesive containing licorice extract three times a day for seven days

Sponsors

Vice chancellor for research, Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: Minimum age 18 years; have sufficient knowledge and literacy, oral aphthous ulcers. Exclusion criteria: major and recurrent stomatitis herpetiformis; aphthous ulcers and other patients who have the buccal mucosa and lips; systemic disease; those taking immunosuppressant drugs during the past month denture wearers; recipients of antibiotics; pregnant patients; people who are not able to use the mucoadhesive; aphthous ulcer syndrome is that it is one presentations (Behcet); smokers and those who can not study continue until the end due to personal or social causes.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Severity of pain. Timepoint: 48 hours. Method of measurement: visual analoge scale.;The total size of the wound with erythematous halo. Timepoint: 48 hours. Method of measurement: Periodontal probe.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTahereh Molania

Mazandaran University of Medical Sciences

T_molania117@yahoo.com+98 11 3330 2908

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026