Skip to content

The Effect of Ziziphus jujuba Syrup on the Incidence and Severity of Symptoms of Upper Respiratory Tract Infections

The Effect of Ziziphus jujuba Syrup on the Incidence and Severity of Symptoms of Upper Respiratory Tract Infections in University Students: A Randomized Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170313033047N5
Enrollment
100
Registered
2026-01-05
Start date
2025-12-31
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper respiratory tract infection (URTI). Acute upper respiratory infection, unspecified

Interventions

Intervention 1: Intervention group: In the intervention group, jujube syrup will be administered. Participants will be instructed to consume the syrup nightly for 30 consecutive nights at a fixed time

Sponsors

Shahed University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 28 Years

Inclusion criteria

Inclusion criteria: Healthy students without an active upper respiratory tract infection at the time of study entry, as determined based on the students’ self-reported symptoms of infection, the research instrument, and clinical examination by a physician from the research team.

Exclusion criteria

Exclusion criteria: The presence of major underlying conditions (such as diabetes or immunodeficiency) that may affect the immune system, as self-reported by the student. Receipt of the influenza vaccine during the current year. Current use of antihistamine medications.

Design outcomes

Primary

MeasureTime frame
Incidence of upper respiratory tract infection. Timepoint: Before the intervention, on the 10th day, and on the 30th day of the intervention. Method of measurement: Wisconsin Upper Respiratory Symptom Survey – 21 questionare.;Severity of upper respiratory tract infection. Timepoint: After the onset of a cold or influenza (confirmed by the research team physician), it will be measured daily until the resolution of the illness. Method of measurement: Wisconsin Upper Respiratory Symptom Survey – 21 questionare.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Jadid-Milani

Shahed University

milani@shahed.ac.ir+98 21 5121 2130

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026