Term pergnancy.
Conditions
Interventions
Intervention 1: 40 mg Isosorbide Mononitrate will be given ever 6 hours in 3 dose At intervals of 0, 6 and 12 hours. Intervention 2: 25 µg misoprostol will be given ever 6 hours in 3 dose At interva
Treatment - Drugs
40 mg Isosorbide Mononitrate will be given ever 6 hours in 3 dose At intervals of 0, 6 and 12 hours.
25 µg misoprostol will be given ever 6 hours in 3 dose At intervals of 0, 6 and 12 hours.
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: term pregnancy having indication for termination; Bishop score less than 6; not using another method for cervical ripening. Exclusion criteria: preterm pregnancies; Bishop-score of 6; coagulation disorder; Cesarean section; severe preeclampsia; primary hypo tension; any type of heart disease; using any medication for heart disease, anticoagulants, contortionists and history for adrenal disease.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Apgar score. Timepoint: after intervention. Method of measurement: According to expert examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Bishop Scale. Timepoint: After intervention. Method of measurement: According to expert examination.;Effective time. Timepoint: After intervention. Method of measurement: Hours.;Hypertension et contractions. Timepoint: After intervention. Method of measurement: According to expert examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMarzieh Lotfalizade
Mashhad University of Medical Sciences
Outcome results
None listed