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Comparison the analgesic effect of nebulized fentanyl and infusion of ketamine for pain management in patients with long bone fractures in a clinical trial

Comparison the analgesic effect of nebulized fentanyl and infusion of ketamine for pain management of long bone fractures

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017031229801N2
Enrollment
136
Registered
2017-06-17
Start date
2017-01-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Long bone fractures. Disorders of continuity of bone

Interventions

Intervention 1: Intervention group: For first group 5 mL of saline intravenously and 4 micrograms per kilogram of solution, 50 micrograms per ml of fentanyl that its volume with normal saline arrives
Treatment - Drugs
Intervention group: For first group 5 mL of saline intravenously and 4 micrograms per kilogram of solution, 50 micrograms per ml of fentanyl that its volume with normal saline arrives to 5 cc, receive
Intervention group: for the second group 0.4 mg/kg ketamine within 10 minutes will be infused.

Sponsors

Vice Chancellor For Research Of Ahvaz Jundishapur University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 18 to 55 years Exclusion criteria: passing more than 24 hours of fractures; Avulsion fractures; head injury (if the level of consciousness decreased ); a history of smoking or drug abuse; pregnancy and lactation; signs of alcohol ( alcoholic patients ); loss of consciousness; difficulty in breathing; allergy to ketamine; a history of seizures

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Before the intervention, and (5, 10, 15, 30 and 60 minutes) after intervention. Method of measurement: Visual pain scale.

Secondary

MeasureTime frame
Medication side effects. Timepoint: (5, 10, 15, 30 and 60 ) minutes after intervention. Method of measurement: vital signs monitoring and symptoms created after the intervention.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Afsaneh khazaeli

Department of Emergency Medicine

A65khazaeli@gmail.com+98 61 3338 1581

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026