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Effect Of Vaginal Cream Glycyrrihiza Glabra On Improvement Of Symptoms Of Fungal Vulvovaginitis

Effect Of Vaginal Cream Glycyrrihiza Glabra On Improvement Of Symptoms Of Fungal Vulvovaginitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017031133008N1
Enrollment
60
Registered
2017-04-03
Start date
2017-04-04
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

candidal vulvovaginitis. Candidiasis of vulva and vagina

Interventions

Intervention 1: vaginal cream licorice 50ml,one Applicator for7day. Intervention 2: vaginal cream clotrimazol 1%,one Applicator for7day.
Treatment - Drugs
vaginal cream licorice 50ml,one Applicator for7day
vaginal cream clotrimazol 1%,one Applicator for7day

Sponsors

Vice chancellor for research of Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 49 Years

Inclusion criteria

Inclusion criteria: Including criteria consisted of: Women at reproductive age of 15 to 45 years old ?. married ?. not being pregnant, menopause, and breast feeding ?. having at least two symptoms of vaginal candidiasis in interview( observed and being confirmed by laboratory studies) ?. Lack of chronic diseases such as disorders that weaken the immune system, blood pressure, and diabetes ?. no use of Chemical and herbal antifungal drugs during the last two weeks ?. not having other vaginal infection such as trichomonas vaginitis, bacterial and mixtures ?. not using vaginal creams and suppositories during the 48 hours before starting of the study ?. not participating in another research study, simultaneously with this study ?. lack of allergy to licorice ?. lack of use of broad-spectrum antibiotics and corticosteroids during the last two weeks for any medical proposes . Exclusion criteria consisted of: getting pregnant during the study ?. allergy to licorice ?. obligation to use of antibiotics for treatment of systemic infections other than vaginitis during the study ?. Failure to adhere to the correct pattern of the treatment (forgetting the drug for more than one night).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Vaginal sores and lesions. Timepoint: 1,7,14day. Method of measurement: positive,negetive.;Vaginal redness. Timepoint: 1,7,14day. Method of measurement: positive,negetive.;Itching genitals. Timepoint: 1,7,14. Method of measurement: positive,negetive.;Dysuria. Timepoint: 1,7,14 day. Method of measurement: positive,negetive.;Cheesy white secretions. Timepoint: 1,7,14day. Method of measurement: positive,negetive.;Dyspareunia. Timepoint: 1,7,14. Method of measurement: positive,negetive.;Red vagina is with white discharge. Timepoint: 1,7,14day. Method of measurement: positive,negetive.;Papulopustular damagesand. Timepoint: 1,7,14. Method of measurement: positive,negetive.;Abnormal cervical. Timepoint: 1,7,14day. Method of measurement: positive,negetive.;Laboratory evaluation. Timepoint: 1,7,14day. Method of measurement: positive,negetive.

Secondary

MeasureTime frame
Licorice sensitivity. Timepoint: 1,7,14. Method of measurement: positive,negetive.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNeda Dodange Balakhani

Iran university of medical science

Neda.dod@gmail.com+98 21 8888 2885

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026