Recurrent aphthous ulcer. Recurrent oral aphthae
Conditions
Interventions
Intervention 1: Intervention group 1: Mucoadhesive with mulberry juice, three times a day for seven days. Intervention 2: Intervention group 2: Mucoadhesive without medicine, three times a day for sev
Treatment - Drugs
Placebo
Intervention group 1: Mucoadhesive with mulberry juice, three times a day for seven days
Intervention group 2: Mucoadhesive without medicine, three times a day for seven days
Sponsors
Vice Chancellor for Research and Technology, Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:Patients with minor aphthous stomatitis; over 18 years old. Exclusion criteria:major and recurrent stomatitis herpetiformis; patients who have aphthous ulcers other than buccal mucosa and lips; having systemic disease; those taking immunosuppressant drugs during the past month; denture wearers; recipients of antibiotics; pregnant patients; people who are not able to use the mucoadhesive; aphthous ulcers which are the manifestation of a syndrome (Behcet); smokers and those who can not complete the study until the end due to personal or social causes.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of pain. Timepoint: Zero, three, five and seven days after the treatment. Method of measurement: Visual Analogue Scale.;The total size of the ulcer with erythmatous halo. Timepoint: Zero, three, five and seven days after the treatment. Method of measurement: Periodontal probe. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSomayeh Shahani
Mazandaran University of Medical Sciences
Outcome results
None listed