Comparison of triamcinolone and dextrose prolotherapy in patients with knee osteoarthritis

The effect of intra articular injection of triamcinolone in comparison with dextrose prolotherapy on pain and function of patients with knee osteoarthritis, single blind clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170311033000N4

Enrollment

Registered

2020-04-23

Start date

2019-01-30

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis. M17

Interventions

Intervention 1: Intervention group: Intervention group 1: triamcinolone, knee intraarticular injection, 40 mg 1 time. Intervention 2: Intervention group: Single dextrose prolotherapy as an intra-artic

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: arthralgia since the past 3 months; radiologic evidence of articular damage (grade 2,3 of Kellgren-Lawrence scale) based on knee OA criteria of ACR and age between 45-75 years.

Exclusion criteria

Exclusion criteria: Exclusion criteria: systemic diseases such as rheumatoid arthritis (RA), any history of intera articular injection, knee surgery or physiotherapy in the last 3 months.

Design outcomes

Primary

Measure	Time frame
Knee pain. Timepoint: Before intervention,1 months & 3 months after intervention. Method of measurement: WOMAC questionnaire.;Joint Stiffness. Timepoint: Before intervention, 1 months & 3 months after intervention. Method of measurement: WOMAC questionnaire.;Function. Timepoint: Before intervention, 1 months & 3 months after intervention. Method of measurement: WOMAC questionnaire.;The maximum distance of walking. Timepoint: ????Before intervention, 1 months & 3 months after intervention. Method of measurement: Lequesne Index.;Activity of daily living. Timepoint: ????Before intervention, 1 months & 3 months after intervention. Method of measurement: Lequesne Index.	—

Measure

Time frame

Knee pain. Timepoint: Before intervention,1 months & 3 months after intervention. Method of measurement: WOMAC questionnaire.;Joint Stiffness. Timepoint: Before intervention, 1 months & 3 months after intervention. Method of measurement: WOMAC questionnaire.;Function. Timepoint: Before intervention, 1 months & 3 months after intervention. Method of measurement: WOMAC questionnaire.;The maximum distance of walking. Timepoint: ????Before intervention, 1 months & 3 months after intervention. Method of measurement: Lequesne Index.;Activity of daily living. Timepoint: ????Before intervention, 1 months & 3 months after intervention. Method of measurement: Lequesne Index.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Modabberi

Shahid Beheshti University of Medical Sciences

mohsen_modabberi@yahoo.com0098113204024

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026